Publications

Latest publications

 

  1. D’Agostino F.; Vliora M.; Grillo E;  Corsini M.; Ravelli C.; Simonetto A;  Gilioli G.;  Mitola S;  Flouris A.D Impacts of obesity and obesogenic behaviours on climate change: a systematic review protocol .Open Research Europe 2024-08-05 | Journal article DOI: 10.12688/openreseurope.17265.1

  2. Ravelli C, Corsini M, Ventura A., Domenichini M., Grillo E., Mitola S.  Alternative method to visualize receptor dynamics in cell membranes.  PLoS One 2024 Jul 29;19(7):e0308231.  doi: 10.1371/journal.pone.0308231.

  3.  Codenotti S, Sandrini L, Mandracchia D, Lorenzi L, Corsetti G, Poli M, Asperti M, Salvi V, Bosisio D, Monti E, Mitola S, Triggiani L, Guescini M, Pozzo E, Sampaolesi M, Gastaldello S, Cassandri M, Marampon F, Fanzani A. Statin-Sensitive Akt1/Src/Caveolin-1 Signaling Enhances Oxidative Stress Resistance in Rhabdomyosarcoma.Cancers (Basel). 2024  DOI: 10.3390/cancers16050853

  4. Capoferri D, Bignotti E, Ravaggi A, Mitola S, Romani C.Finding the junction between claudins and endometrial carcinoma.Biochim Biophys Acta Rev Cancer. 2023. DOI: 10.1016/j.bbcan.2023.189019
  5. Domenichini M, Ravelli C, Corsini M, Codenotti S, Moreschi E, Gogna A, Capoferri D, Zizioli D, Bresciani R, Grillo E, Mitola S.The D647N mutation of FGFR1 induces ligand-independent receptor activation.Biochim Biophys Acta Gen Subj. 2023. DOI: 10.1016/j.bbagen.2023.130470
  6. Mignani L, Facchinello N, Varinelli M, Massardi E, Tiso N, Ravelli C, Mitola S, Schu P, Monti E, Finazzi D, Borsani G, Zizioli D.Deficiency of AP1 Complex Ap1g1 in Zebrafish Model Led to Perturbation of Neurodevelopment, Female and Male Fertility; New Insight to Understand Adaptinopathies. Int J Mol Sci. 2023. DOI: 10.3390/ijms24087108
  7. Serpelloni M, Arricca M, Ravelli C, Grillo E, Mitola S, Salvadori A, Mechanobiology of the relocation of proteinin advecting cells: in vitro experiments, multi-physics modeling and simulations. Biomech Model Mechanobiol. 2023. DOI: 10.1007/s10237-023-01717-2
  8. Corsini M. and S. Mitola, Alternative in vivo models to study teratoma. Methods Mol Biol. 2023. DOI:10.1007/978-1-0716-2703-7_14 
  9. Vliora, M., C. Ravelli, E. Grillo, M. Corsini, A. Flouris and S. Mitola, The impact of adipokines on vascular networks in adipose tissue. Cytokine Growth Factor Rev, 2023. DOI: 10.1016/j.cytogfr.2022.07.008. ISSN: 1359-6101 (Electronic)
  10. Grillo, E., C. Ravelli, G. Colleluori, F. D’Agostino, M. Domenichini, A. Giordano, and S. Mitola, Role of gremlin-1 in the pathophysiology of the adipose tissues. Cytokine Growth Factor Rev, 2023. DOI: 10.1016/j.cytogfr.2022.09.004. ISSN: 1879-0305 (Electronic)
  11. Codenotti, S., D. Zizioli, L. Mignani, S. Rezzola, G. Tabellini, S. Parolini, A. Giacomini, M. Asperti, M. Poli, D. Mandracchia, M. Vezzoli, S. Bernardi, D. Russo, S. Mitola, E. Monti, L. Triggiani, D. Tomasini, S. Gastaldello, M. Cassandri, R. Rota, F. Marampon, and A. Fanzani, Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibitors. Cells, 2022. 11(18). DOI: 10.3390/cells11182859. ISSN: 2073-4409 (Electronic)
  12. Vliora, M., E. Nintou, E. Karligiotou, L.G. Ioannou, E. Grillo, S. Mitola, and A.D. Flouris, Implication of Irisin in Different Types of Cancer: A Systematic Review and Meta-Analysis. Int J Mol Sci, 2022. 23(17). DOI: 10.3390/ijms23179971. ISSN: 1422-0067 (Electronic)
  13. Marchetti, L., D. Porciani, S. Mitola, and C. Giacomelli, Editorial: Molecular Insights Into Ligand-Receptor Interactions on the Cell Surface. Front Mol Biosci, 2022. 9: p. 921677. DOI: 10.3389/fmolb.2022.921677. ISSN: 2296-889X (Print)
  14. Mitola, S., C. Ravelli, M. Corsini, A. Gianoncelli, F. Galvagni, K. Ballmer-Hofer, M. Presta, and E. Grillo, Production and Biochemical Characterization of Dimeric Recombinant Gremlin-1. Int J Mol Sci, 2022. 23(3). DOI: 10.3390/ijms23031151. ISSN: 1422-0067 (Electronic)
  15. Vliora, M., E. Grillo, M. Corsini, C. Ravelli, E. Nintou, E. Karligiotou, A.D. Flouris, and S. Mitola, Irisin regulates thermogenesis and lipolysis in 3T3-L1 adipocytes. Biochim Biophys Acta Gen Subj, 2022. 1866(4): p. 130085. DOI: 10.1016/j.bbagen.2022.130085. ISSN: 1872-8006 (Electronic)
  16. Grillo, E., C. Ravelli, M. Corsini, C. Gaudenzi, L. Zammataro, and S. Mitola, Novel potential oncogenic and druggable mutations of FGFRs recur in the kinase domain across cancer types. Biochim Biophys Acta Mol Basis Dis, 2021: p. 166313. DOI: 10.1016/j.bbadis.2021.166313. ISSN: 1879-260X (Electronic)
  17. Romani, C., D. Capoferri, E. Grillo, M. Silvestri, M. Corsini, L. Zanotti, P. Todeschini, A. Ravaggi, E. Bignotti, F. Odicino, E. Sartori, S. Calza, and S. Mitola, The Claudin-Low Subtype of High-Grade Serous Ovarian Carcinoma Exhibits Stem Cell Features. Cancers (Basel), 2021. 13(4). DOI: 10.3390/cancers13040906. ISSN: 2072-6694 (Print)
  18. Corsini M, Ravelli C, Grillo E and Mitola S. The Metastatic Capacity of Melanoma Reveals Alternative Pathways of Cancer Dissemination. Int J transl Med, 2021, 1,163–174. DOI: 10.3390/ijtm1030012. ISSN: 2673-8937
  19. Sacco, A., C. Federico, K. Todoerti, B. Ziccheddu, V. Palermo, A. Giacomini, C. Ravelli, F. Maccarinelli, G. Bianchi, A. Belotti, R. Ribolla, V. Favasuli, A.S. Revenko, A.R. Macleod, B. Willis, H. Cai, J. Hauser, C. Rooney, S.E. Willis, P.L. Martin, A. Staniszewska, H. Ambrose, L. Hanson, C. Cattaneo, A. Tucci, G. Rossi, R. Ronca, A. Neri, S. Mitola, N. Bolli, M. Presta, M. Moschetta, S. Ross, and A.M. Roccaro, Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited antitumor activity. Blood, 2021. 138(18): p. 1705-1720. DOI: 10.1182/blood.2020010572. ISSN: 1528-0020 (Electronic)
  20. Grillo, E., C. Ravelli, M. Corsini, L. Zammataro, and S. Mitola, Protein domain-based approaches for the identification and prioritization of therapeutically actionable cancer variants. Biochim Biophys Acta Rev Cancer, 2021: p. 188614. DOI: 10.1016/j.bbcan.2021.188614. ISSN: 1879-2561 (Electronic)
  21. Grillo, E., M. Corsini, C. Ravelli, L. Zammataro, M. Bacci, A. Morandi, E. Monti, M. Presta, and S. Mitola, Expression of activated VEGFR2 by R1051Q mutation alters the energy metabolism of Sk-Mel-31 melanoma cells by increasing glutamine dependence. Cancer Lett, 2021. 507: p. 80-88. DOI: 10.1016/j.canlet.2021.03.007. ISSN: 1872-7980 (Electronic)
  22. Asperti, M., S. Bellini, E. Grillo, M. Gryzik, L. Cantamessa, R. Ronca, F. Maccarinelli, A. Salvi, G. De Petro, P. Arosio, S. Mitola, and M. Poli, H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis. Free Radic Biol Med, 2021. 169: p. 294-303. DOI: 10.1016/j.freeradbiomed.2021.04.024. ISSN: 1873-4596 (Electronic)
  23. Scutera, S., S. Mitola, R. Sparti, V. Salvi, E. Grillo, G. Piersigilli, M. Bugatti, D. Alotto, T. Schioppa, S. Sozzani, and T. Musso, Bartonella henselae Persistence within Mesenchymal Stromal Cells Enhances Endothelial Cell Activation and Infectibility That Amplifies the Angiogenic Process. Infect Immun, 2021. 89(8): p. e0014121. DOI: 10.1128/IAI.00141-21. ISSN: 1098-5522 (Electronic)
  24. Grillo, E., M. Corsini, C. Ravelli, M. di Somma, L. Zammataro, E. Monti, M. Presta, and S. Mitola, A novel variant of VEGFR2 identified by a pan-cancer screening of recurrent somatic mutations in the catalytic domain of tyrosine kinase receptors enhances tumor growth and metastasis. Cancer Lett, 2021. 496: p. 84-92. DOI: 10.1016/j.canlet.2020.09.027. ISSN: 1872-7980 (Electronic)
  25. Bogale, T.A., G. Faustini, F. Longhena, S. Mitola, M. Pizzi, and A. Bellucci, Alpha-Synuclein in the Regulation of Brain Endothelial and Perivascular Cells: Gaps and Future Perspectives. Front Immunol, 2021. 12: p. 611761. DOI: 10.3389/fimmu.2021.611761. ISSN: 1664-3224 (Electronic)
  26. Corsini, M., C. Ravelli, E. Grillo, P. Dell’Era, M. Presta, and S. Mitola, Simultaneously characterization of tumoral angiogenesis and vasculogenesis in stem cell-derived teratomas. Exp Cell Res, 2021. 400(2): p. 112490. DOI: 10.1016/j.yexcr.2021.112490. ISSN: 1090-2422 (Electronic)
  27. Corsini, M., E. Moroni, C. Ravelli, E. Grillo, M. Presta, and S. Mitola, In Situ DNA/Protein Interaction Assay to Visualize Transcriptional Factor Activation. Methods Protoc, 2020. 3(4). DOI: 10.3390/mps3040080. ISSN: 2409-9279 (Electronic)
  28. Ciccarese, F., A. Grassi, L. Pasqualini, S. Rosano, A. Noghero, F. Montenegro, F. Bussolino, B. Di Camillo, L. Finesso, G.M. Toffolo, S. Mitola, and S. Indraccolo, Genetic perturbation of IFN-alpha transcriptional modulators in human endothelial cells uncovers pivotal regulators of angiogenesis. Comput Struct Biotechnol J, 2020. 18: p. 3977-3986. DOI: 10.1016/j.csbj.2020.11.048. ISSN: 2001-0370 (Print)
  29. Romani, C., V. Zizioli, M. Silvestri, L. Ardighieri, M. Bugatti, M. Corsini, P. Todeschini, S. Marchini, M. D’Incalci, L. Zanotti, A. Ravaggi, F. Facchetti, A. Gambino, F. Odicino, E. Sartori, A.D. Santin, S. Mitola, E. Bignotti, and S. Calza, Low Expression of Claudin-7 as Potential Predictor of Distant Metastases in High-Grade Serous Ovarian Carcinoma Patients. Front Oncol, 2020. 10: p. 1287. DOI: 10.3389/fonc.2020.01287. ISSN: 2234-943X (Print)
  30. Amodeo, R., D. Convertino, M. Calvello, L. Ceccarelli, F. Bonsignore, C. Ravelli, A. Cattaneo, C. Martini, S. Luin, S. Mitola, G. Signore, and L. Marchetti, Fluorolabeling of the PPTase-Related Chemical Tags: Comparative Study of Different Membrane Receptors and Different Fluorophores in the Labeling Reactions. Front Mol Biosci, 2020. 7: p. 195. DOI: 10.3389/fmolb.2020.00195. ISSN: 2296-889X (Print)
  31. Gonzalez-Gonzalez, A., A. Gonzalez, N. Rueda, C. Alonso-Gonzalez, J.M. Menendez, C. Martinez-Campa, S. Mitola, and S. Cos, Usefulness of melatonin as complementary to chemotherapeutic agents at different stages of the angiogenic process. Sci Rep, 2020. 10(1): p. 4790. DOI: 10.1038/s41598-020-61622-x. ISSN: 2045-2322 (Electronic)
  32. Nawaz, M.I., S. Rezzola, C. Tobia, D. Coltrini, M. Belleri, S. Mitola, M. Corsini, A. Sandomenico, A. Caporale, M. Ruvo, and M. Presta, D-Peptide analogues of Boc-Phe-Leu-Phe-Leu-Phe-COOH induce neovascularization via endothelial N-formyl peptide receptor 3. Angiogenesis, 2020. 23(3): p. 357-369. DOI: 10.1007/s10456-020-09714-0. ISSN: 1573-7209 (Electronic)